FIG. 8.

(A) Bovine TE and EXP synovium, as well as human OA EXPs, showed elevated nitric oxide production in response to IL treatment, *p < 0.05 versus CTL, ^†p < 0.05 versus DEX. (B) Elevated CD14 expression (reddish brown) was observed in both TE and EXP tissue treated with IL. An increase was also seen in CTL groups, but CD14 staining was less intense for DEX specimens in both tissue types. (C) The phenotype ratio of MLS (CD14⁺) to FLS (CD14⁻) in EXP tissue was maintained by DEX. In CTL- and IL-treated tissue, MLS content increased and FLS content decreased. Total cell content increased with IL treatment; *p < 0.05 (total DNA), ^†p < 0.05 (FLS), ^‡p < 0.05 (MLS).