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(A) The median energy expenditure (EE) increased from the hypothyroid to the euthyroid condition at warm temperatures by 113 kcal/day (8.5%; p = 0.0002) and after cooling by 211 kcal/day (15%; p < 0.0001). (B) Cold-induced thermogenesis (CIT) rose by 56 kcal/day (102%; p = 0.011) after thyroid hormone replacement compared to the hypothyroid state. ***p < 0.001; *p < 0.05.
