Table 4.
Related variables in chow- and HMD fed and HMD + soluble epoxide hydrolase inhibitor (TPPU) mice
| Variable Index | Chow Diet | HMD | HMD+TPPU |
|---|---|---|---|
| Body weight, g | 25.09 ± 0.84 | 25.44 ± 0.43 | 25.39 ± 0.66 |
| Liver/body | |||
| Weight ratio | 0.038 ± 0.000 | 0.046 ± 0.000** | 0.043 ± 0.000# |
| Plasma Hcy, µM | 3.13 ± 0.87 | 27.79 ± 3.71** | 25.90 ± 4.95 |
| Plasma TG, mM | 0.54 ± 0.07 | 0.50 ± 0.05 | 0.52 ± 0.09 |
| Plasma Chol, mM | 1.76 ± 0.09 | 1.79 ± 0.09 | 1.94 ± 0.13 |
Values are means ± SE; n = 5 for chow diet; n = 7 for high-metnionine diet (HMD); and n = 8 for HMD + 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU). C57BL/6 mice were fed a chow diet or HMD for 8 wk with or without TPPU in drinking water (0.8 mg·kg−1·day−1) for 4 wk. Hcy, homocysteine; TG, triglyceride; Chol, cholesterol.
**
P < 0.01 vs. chow diet;
#
P < 0.01 vs. HMD.