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Mifepristone (MPF) effects on glycerol-induced p21 gene induction (p21 mRNA) and renal p21 accumulation. MFP markedly diminished post-glycerol p21 protein and mRNA increases 4 h after glycerol + MFP injection. Conversely, MFP did not significantly impact p21 expression in non-glycerol-injected (normal) mice. Values are means ± SE; n = 4 mice group. NS, not significant.
