Fig. 2.

Selective stimulation of the P2Y₂ receptor increases urinary Na⁺ excretion (U_NaV). Individual data points and means ± SE are shown for 24-h Na⁺ excretion for B6 mice maintained on a Na⁺-free diet before and after treatment with vehicle (n = 7 cages with 3 animals/cage for a total of 21 female mice, each tested once) or MRS2768 (n = 7 cages with 3 animals/cage for a total of 6 male and 15 female mice, each tested once). *Significantly greater than Na⁺-free diet and vehicle treatment (by one-way ANOVA with a Tukey’s honest significant difference post hoc test).