Table 2.
The association between RGS5 and various clinicopathologic factors
| RGS5 expression | |||
|---|---|---|---|
| Characteristics | High expression | Low expression | P value |
| No. of patients | 20 | 23 | |
| Age (years) | 0.6059 | ||
| ≦70 | 11 | 8 | |
| 70< | 12 | 12 | |
| Gender | 0.6386 | ||
| Male | 11 | 11 | |
| Female | 12 | 9 | |
| Tumor size | 0.9202 | ||
| <20 | 13 | 9 | |
| 20≦ | 10 | 11 | |
| T classification | 0.4373 | ||
| T1 | 10 | 11 | |
| T2 | 12 | 9 | |
| T3 | 1 | 0 | |
| N classification | 0.6313 | ||
| N0 | 21 | 19 | |
| N1 + N2 | 2 | 1 | |
| Pattern of invasion | 0.0037 | ||
| Expansive type | 1 | 6 | |
| Intermediate type | 10 | 12 | |
| Infiltrative type | 12 | 2 | |
| Differentiation | 0.1667 | ||
| Well | 17 | 18 | |
| Moderate + Poor | 6 | 2 | |
| Depth of invasion (mm) | 0.0463 | ||
| <4 | 8 | 13 | |
| 4≦ | 15 | 7 | |
| Lymphatic vessel invasion | 0.0238 | ||
| Absent | 16 | 19 | |
| Present | 7 | 1 | |
| Vascular invasion | 0.5689 | ||
| Absent | 18 | 17 | |
| Present | 5 | 3 | |
| Lymph node metastasis after surgery | 0.1684 | ||
| Absent | 9 | 4 | |
| Present | 14 | 16 | |
| p16 | 0.2321 | ||
| Absent | 16 | 17 | |
| Present | 7 | 3 | |
Note. RGS5: regulator of G‐protein signaling 5; Well: well‐differentiated squamous cell carcinoma; Moderate: moderately differentiated squamous cell carcinoma; Poor: poorly differentiated squamous cell carcinoma.