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. 2018 Nov 18;100(4):1066–1072. doi: 10.1093/biolre/ioy245

Table 2.

Quantification of ovarian follicle number at different development stages of Per1m/m; Per2m/m doubly mutant and control mice (3, 8, 26, 52 weeks old).

Ovarian follicle stages Ovarian follicle number (3 weeks old) n (Per1m/m;Per2m/m) n (Control) P value
Per1m/m;Per2m/m Control
Ovarian follicle number (3 weeks old)
Primordial 1356.00 ± 307.05 1642.00 ± 634.34 5 5 0.39068631
Primary 162.00 ± 23.61 165.00 ± 53.85 5 5 0.911982313
Secondary 343.00 ± 102.02 337.00 ± 45.36 5 5 0.90731292
Antral 55.00 ± 12.75 53.00 ± 54.15 5 5 0.937904244
Total 1916.00 ± 370.18 2197.00 ± 692.08 5 5 0.446499944
Ovarian follicle number (8 weeks old)
Ovarian follicle stages Ovarian follicle number (8 weeks old) n (Per1m/m;Per2m/m) n (Control) P value
Per1m/m;Per2m/m Control
Primordial 151.67 ± 80.04 222.00 ± 95.43 9 5 0.185634764
Primary 177.78 ± 57.29 177.00 ± 61.85 9 5 0.98228293
Secondary 211.11 ± 70.70 174.00 ± 86.16 9 5 0.422737236
Antral 91.11 ± 24.21 61.00 ± 25.38 9 5 0.057257555
Total 631.67 ± 172.92 634.00 ± 248.26 9 5 0.984694705
Ovarian follicle number (26 weeks old)
Ovarian follicle stages Ovarian follicle number (26 weeks old) n (Per1m/m;Per2m/m) n (Control) P value
Per1m/m;Per2m/m Control
Primordial 60.00 ± 43.09 95.91 ± 41.76 11 8 0.085424818
Primary 94.38 ± 51.79 148.18 ± 40.64 11 8 0.021065468
Secondary 72.50 ± 35.36 138.18 ± 24.73 11 8 0.000173887
Antral 41.88 ± 13.61 53.64 ± 32.41 11 8 0.350178113
Total 268.75 ± 103.71 435.91 ± 85.81 11 8 0.001301834
Ovarian follicle number (52-week-old)
Ovarian follicle stages Ovarian follicle number (52 weeks old) n (Per1m/m;Per2m/m) n (Control) P value
Per1m/m;Per2m/m Control
Primordial 27.14 ± 19.19 51.25 ± 35.87 14 12 0.039192918
Primary 25.00 ± 19.12 52.50 ± 12.88 14 12 0.000299226
Secondary 23.93 ± 11.12 41.67 ± 25.35 14 12 0.026081444
Antral 12.14 ± 7.26 22.50 ± 13.23 14 12 0.018619029
Total 88.21 ± 48.70 167.92 ± 59.29 14 12 0.00095254