4. Amifostine: comparison of different doses (other outcomes).

Outcome	Study ID	Time point	Amifostine 3 times weekly	Amifostine 5 times weekly	Results	Comments
Quality of life	Jellema 2006	Assessed at end of RT and 6, 12, 18 and 24 months after RT	No data	No data	"No significant differences between the 3 treatment arms"
Nausea	Jellema 2006		9/30	14/30	RR 0.64 (95% CI 0.33 to 1.25); P = 0.19
Vomiting	Jellema 2006		2/30	8/30	RR 0.25 (95% CI 0.06 to 1.08); P = 0.06
Allergic response	Jellema 2006		2/30	2/30	RR 1.00 (95% CI 0.15 to 6.64); P = 1

CI = confidence interval; RR = risk ratio; RT = radiotherapy.