9. Bethanechol versus artificial saliva (other outcomes).

Outcome	Study ID	Time point	Bethanechol	Artificial saliva	Results	Comments
Lacrimation (watering eyes)	Jham 2007	End of RT	3/22	0/21	RR 6.70 (95% CI 0.37 to 122.29); P = 0.2
Nervousness			3/22	0/21	RR 6.70 (95% CI 0.37 to 122.29); P = 0.2
Frequent urination			3/22	0/21	RR 6.70 (95% CI 0.37 to 122.29); P = 0.2
Sweating			2/22	0/21	RR 4.78 (95% CI 0.24 to 94.12); P = 0.3	"1 patient using bethanechol dropped out of the study due to excessive sweating (Grade 2 severity; National Cancer Institute Common Terminology Criteria for Adverse Events – NCI CTCAE, v 3"
Warm face			2/22	0/21	RR 4.78 (95% CI 0.24 to 94.12); P = 0.3
Cramps			1/22	0/21	RR 2.87 (95% CI 0.12 to 66.75); P = 0.51
Diarrhoea			1/22	0/21	RR 2.87 (95% CI 0.12 to 66.75); P = 0.51
Nausea			1/22	2/21	RR 0.48 (95% CI 0.05 to 4.88); P = 0.53

CI = confidence interval; RR = risk ratio; RT = radiotherapy.