Comparison 8. Bethanechol versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Xerostomia (0 to 3 scale ‐ grade 2 or above)	1		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 End of radiotherapy	1	84	Risk Ratio (M‐H, Random, 95% CI)	0.43 [0.28, 0.66]
1.2 Up to and including 3 months postradiotherapy	1	84	Risk Ratio (M‐H, Random, 95% CI)	0.81 [0.65, 1.01]
2 Salivary flow rate (unstimulated) ‐ ml/min	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
2.1 2 months postradiotherapy	1	97	Mean Difference (IV, Random, 95% CI)	0.19 [0.06, 0.32]
3 Salivary flow rate (stimulated) ‐ ml/min	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
3.1 2 months postradiotherapy	1	97	Mean Difference (IV, Random, 95% CI)	0.15 [‐0.03, 0.33]