Table 4. Performance of laboratory parameters for determining active disease.
| Variables | Cut-off values |
Sensitivity (95% CI) |
Specificity (95% CI) |
Accuracy (95% CI) |
|---|---|---|---|---|
| CRP (mg/L) | ≥30 | 77% (64%-87%) | 93% (84%-97%) | 86% (78%-91%) |
| WCC (×103/μL) | ≥11,000 | 71% (58%-82%) | 85% (73%-92%) | 78% (70%-85%) |
| ESR (mm/h) | ≥42 | 79% (65%-88%) | 67% (54%-78%) | 72% (63%-80%) |
| Hematocrit (%) | <35 | 60% (46%-72%) | 76% (64%-85%) | 69% (59%-76%) |
| OD of anti-IFN- | ≥3.5 | 77% (64%-86%) | 58% (45%-69%) | 67% (58%-75%) |
| γ auto-Abs |
Abbreviations: CI, confidence interval; CRP, C-reactive protein; WCC, white cell count; ESR, erythrocyte sedimentation rate; OD, optical density; anti-IFN-γ auto-Abs; anti-interferon-γ autoantibodies