Table 4. Dose of cisplatin estimated to cause nephrotoxicity in 32 risk groups.
Group | Pre_scra(mg/dL) | BMIb (kg/m2) | MgOc | NSAIDsd | Cisplatin dose estimated to cause nephrotoxicity (mg/m2) |
---|---|---|---|---|---|
1 |
0.56 first quartile (0–25%) |
22.27 above the median |
with | with | 50.33# |
2 | without | 68.70 | |||
3 | without | with | 26.58# | ||
4 | without | 44.95# | |||
5 |
17.47 below the median |
with | with | 67.73 | |
6 | without | 86.10 | |||
7 | without | with | 43.98# | ||
8 | without | 62.35 | |||
9 |
0.63 second quartile (25–50%) |
22.27 above the median |
with | with | 57.77# |
10 | without | 76.14 | |||
11 | without | with | 34.02# | ||
12 | without | 52.39# | |||
13 |
17.47 below the median |
with | with | 75.17 | |
14 | without | 93.54 | |||
15 | without | with | 51.42# | ||
16 | without | 69.79 | |||
17 |
0.78 third quartile (50–75%) |
22.27 above the median |
with | with | 73.68 |
18 | without | 92.06 | |||
19 | without | with | 49.93# | ||
20 | without | 68.31 | |||
21 |
17.47 below the median |
with | with | 91.08 | |
22 | without | 109.46 | |||
23 | without | with | 67.33 | ||
24 | without | 85.71 | |||
25 |
0.89 fourth quartile (75–100%) |
22.27 above the median |
with | with | 84.83 |
26 | without | 103.21 | |||
27 | without | with | 61.08 | ||
28 | without | 79.46 | |||
29 |
17.47 below the median |
with | with | 102.23 | |
30 | without | 120.61 | |||
31 | without | with | 78.48 | ||
32 | without | 96.86 |
abaseline serum creatinine,
bbody mass index,
cmagnesium oxide,
dnonsteroidal anti-inflammatory drugs.