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. 2019 Apr 25;14(4):e0215757. doi: 10.1371/journal.pone.0215757

Table 4. Dose of cisplatin estimated to cause nephrotoxicity in 32 risk groups.

Group Pre_scra(mg/dL) BMIb (kg/m2) MgOc NSAIDsd Cisplatin dose estimated to cause nephrotoxicity (mg/m2)
1 0.56
first quartile
(0–25%)
22.27
above the median
with with 50.33#
2 without 68.70
3 without with 26.58#
4 without 44.95#
5 17.47
below the median
with with 67.73
6 without 86.10
7 without with 43.98#
8 without 62.35
9 0.63
second quartile
(25–50%)
22.27
above the median
with with 57.77#
10 without 76.14
11 without with 34.02#
12 without 52.39#
13 17.47
below the median
with with 75.17
14 without 93.54
15 without with 51.42#
16 without 69.79
17 0.78
third quartile
(50–75%)
22.27
above the median
with with 73.68
18 without 92.06
19 without with 49.93#
20 without 68.31
21 17.47
below the median
with with 91.08
22 without 109.46
23 without with 67.33
24 without 85.71
25 0.89
fourth quartile
(75–100%)
22.27
above the median
with with 84.83
26 without 103.21
27 without with 61.08
28 without 79.46
29 17.47
below the median
with with 102.23
30 without 120.61
31 without with 78.48
32 without 96.86

abaseline serum creatinine,

bbody mass index,

cmagnesium oxide,

dnonsteroidal anti-inflammatory drugs.