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. 2017 Jul 12;2017(7):CD011821. doi: 10.1002/14651858.CD011821.pub2

Akhtar 1996.

Methods Country where data collected: India
Parallel‐group RCT
Unit of randomisation: participant
Unit of analysis: participant
Duration: NR
Participants Inclusion criteria: any age, TBSA >10% up to 40%
Exclusion criteria: systemic diseases e.g. diabetes, or malignancy, vitamin deficient and immunosuppressed; electrical, chemical and radiation burns
Participants: 100 patients from tertiary hospital
Mean age (years): NR (comparable between groups)
Male participants: NR (comparable between groups)
Burn type: NR
Burn degree NR (severity comparable between groups)
Burn size (%TBSA): NR (severity comparable between groups, see inclusion criteria)
Burn location: NR (comparable between groups)
Interventions Intervention arm 1: Aloe vera cream every 3rd day. N = 50
Intervention arm 2: framycetin cream every 3rd day. N = 50
Cointerventions: NR
Outcomes Wound healing (mean time to healing)
Notes Reported in abstract form only
Funding NR
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "Allocation to intervention was done by block randomization of 8 subjects."
Comment: no information on how randomisation sequence was generated
Allocation concealment (selection bias) Unclear risk Quote: "Allocation to intervention was done by block randomization of 8 subjects."
Comment: no information on whether allocation to treatment groups was concealed
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Quote "Blinded randomized controlled trial."
Comment: not clear who was blinded
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk No specific quote
Comment: reported in abstract only and unclear whether there was any or significant attrition
Selective reporting (reporting bias) Unclear risk No specific quote; reported in abstract only; unclear if all planned outcomes were reported
Other bias Unclear risk Abstract only, unclear if any additional sources of bias