Bangroo 2005.
| Methods | Country where data collected: India Parallel group RCT Unit of randomisation: participant Unit of analysis: participant Duration: NR |
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| Participants | Inclusion criteria: < 12 years old, superficial thermal burn, < 50% TBSA Exclusion criteria: NR Participants: 64 hospital patients (children) Mean age (years): NR Male participants: 23/32 vs 25/32 Burn type: 56 wet burns, 8 dry burns Burn degree: NR/NA Burn size (%TBSA): < 10% 5 vs 3; 11%‐20% 2 vs 5; 21%‐30% 7 vs 8; 31%‐40% 16 vs 15; 41%‐50% 2 vs 1 Burn location: 12 facial, 20 extremities, 21 trunk and abdomen |
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| Interventions | Intervention arm 1: honey dressing (changed twice daily) N = 32 Intervention arm 2: SSD (dressing changed twice daily) N = 32 Cointervention: Thorough bath, twice daily with tap water and soap; followed by sponging and peeling away dead skin. |
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| Outcomes | Primary outcome: Wound healing (mean time to healing) Secondary outcome: Adverse events |
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| Notes | Funding NR | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Quote: “two groups…. were formed and patients assigned to it randomly” Comment: method of randomisation unclear |
| Allocation concealment (selection bias) | Unclear risk | Quote: “two groups were formed and patients assigned to it randomly” Comment: no information on whether the allocation of participants to interventions was concealed |
| Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Quote: "Culture swabs were taken from the burnt surface on admission, before any treatment was instituted and repeated after 48 h and, thereafter, every 72 h until the wound healed" Comment: no information on whether assessment of healing was conducted by assessors blinded to treatment allocation |
| Incomplete outcome data (attrition bias) All outcomes | Low risk | Quote: "Wound healing took 10 days in 26 patients belonging to group A, while in 6 patients it took 2 weeks or more to heal.....Wound healing took 3 weeks or more in 19 patients belonging to group B." Comment: it appears that all participants (64 randomised) completed the study |
| Selective reporting (reporting bias) | Unclear risk | Comment: no specific quote but the outcomes assessed were not prespecified so it is unclear whether all outcomes assessed were fully reported; the balance of probabilities is that they were. |
| Other bias | Unclear risk | No specific quote but no evidence of other source of bias, but reporting insufficient to be certain |