Jiao 2015.
| Methods | Country where data collected: China Parallel‐group RCT Unit of randomisation: participant Unit of analysis: participant (one wound per participant) Duration: until healed |
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| Participants | Inclusion criteria: fresh burn wound; total burn 10%‐20% TBSA; no other serious injury; no other major diseases (including cancer, brain disease; heart disease; kidney disease; haematological system disease; and infection); admitted to hospital within 24 h of injury Exclusion criteria: NR Participants 76 hospital patients Male/female: 44/76 (24/38 vs 20/38) Age: 18‐58 (36.8 ± 14.2) (36.5 ± 11.8 vs 36.8 ± 13.2 %TBSA: 15.2 (4.3) Burn degree: superficial: 19 vs 22; deep 19 vs 16 All burns were located around knee areas |
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| Interventions | Intervention arm 1: nano‐silver dressing (N =38) Intervention arm 2: ordinary sterile gauze (N = 38) Co‐interventions: human epidermal growth factor was coated on the surface of the wound; dressing was changed every other day |
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| Outcomes | Primary outcome: wound completely healed Primary outcome: infection ‐ bacterial positive rate at different time points Secondary outcome: adverse events; scar hyperplasia |
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| Notes | Paper in Chinese; data extraction and 'Risk of bias' assessment performed by one review author | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Quote: "a randomised table was used" Comment: not clear how the sequence was generated |
| Allocation concealment (selection bias) | Unclear risk | Comment: no details to indicate whether allocation was adequately concealed |
| Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Comment: no details of outcome assessment were given |
| Incomplete outcome data (attrition bias) All outcomes | Low risk | Comment: result section and tables show that all participant data were included in analysis |
| Selective reporting (reporting bias) | Unclear risk | Comment: unclear based on paper; protocol not obtained |
| Other bias | Unclear risk | Comment: no specific quote, no evidence of other sources of bias but reporting insufficient to be certain |