Muangman 2006.
Methods | Country where data collected: Thailand Parallel‐group RCT Unit of randomisation: participant Unit of analysis: participant Duration: NR |
|
Participants | Inclusion criteria: partial‐thickness burns < 25% TBSA Exclusion criteria: NR Participants: 50 people attending burns unit Mean age (years): 38 ± 25 vs 26 ± 27 Male participants: NR Burn type: flame 14 vs 12; scald 9 vs 12; electrical 1 vs 1; chemical 1 vs 0 Burn degree: NR Burn size (%TBSA): 15 ± 7 vs 15 ± 5 Burn location: NR |
|
Interventions | Intervention arm 1: silver‐coated dressing moistened with sterile water (Acticoat), covered with dry dressing. Inner gauze moistened twice daily and silver dressing changed every 3 days Intervention arm 2: SSD and dry gauze dressing changed twice daily Cointerventions: 2 tabs of acetaminophen (paracetamol) (500 mg/tab) before dressing changes |
|
Outcomes | Primary outcome: wound infection Secondary outcome: pain |
|
Notes | Funding NR | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: “Fifty patients were identified and randomized into 2 groups” Comment: no further information on method of randomisation |
Allocation concealment (selection bias) | Unclear risk | Quote: “Fifty patients were identified and randomized into 2 groups” Comment: no further information to indicate concealment of allocation |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Quote: “A swab of wounds was sent for routine culture and sensitivity twice a week. Wounds were observed daily by an experienced burn surgeon for signs of infection such as erythema, induration, purulent discharge and malodor. Swabs were processed by the laboratory and returned results of 1+, 2+, or 3+ bacterial growth, corresponding to light, medium, or heavy growth on the culture plate ” Comment: no information on whether outcome assessors were blinded as to allocation; balance of probabilities based on quote is that assessment was unblinded |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Quote: “Fifty patients were identified and randomized into 2 groups” Comment: no direct quotes on any withdrawals or whether outcome data was used for all 50 patients |
Selective reporting (reporting bias) | High risk | Quote: “Patients were also reviewed for documentation of efficacy of treatment including day of burn wound closure, pain scores, type of cultured organisms, wound colonization and infection, surgical procedures and mortality between both groups” Comment: no information on day of wound burn closure |
Other bias | Unclear risk | Comment: no direct quotes but no evidence of additional sources of bias, but reporting insufficient to be certain |