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. 2017 Jul 12;2017(7):CD011821. doi: 10.1002/14651858.CD011821.pub2

Ning 2008.

Methods Country where data collected: China
Parallel‐group RCT (intra‐individual)
Unit of randomisation: burn
Unit of analysis: burn
Duration: 28 days
Participants Inclusion criteria: deep partial second‐degree burn wounds < 60% TBSA; age 18‐65; presented within 24 h of injury
Exclusion criteria: complications; other disease; pregnancy; multiple trauma or serious comorbidity
Participants: 20 participants with 2 comparable burns
Mean age (years): NR
Male participants: 12/20
Burn type: NR
Burn degree: 2nd degree
Burn size (%TBSA): 24.1 ± 0.2
Burn location: NR
Interventions Intervention arm 1: sodium hypochlorite (Dermacyn) changed every other day. N = 20 burns
Intervention arm 2: SSD changed every other day. N = 20 burns
Cointerventions: NR
Outcomes Primary outcome: wound healing
Secondary outcome: adverse events
Notes Article in Chinese, extracted and assessed for risk of bias by one review author, discussed with a second review author
Funding NR
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Comment: a random component in the sequence generation process was not reported in detail
Allocation concealment (selection bias) Unclear risk Comment: it was not stated how the randomisation sequence was allocated
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Comment: not mentioned
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comment: results section and tables show that all participant data were included in analysis
Selective reporting (reporting bias) Unclear risk Comment: protocol not obtained, based on paper only
Other bias Unclear risk The whole process of conducting this RCT was not clear, including whether the paired data were accounted for in the analysis