Comparison 1. Vitamin E versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Any AMD	4	55614	Risk Ratio (M‐H, Fixed, 95% CI)	0.97 [0.90, 1.06]
2 Late AMD (either neovascular AMD or geographic atrophy or both)	4	55614	Risk Ratio (M‐H, Fixed, 95% CI)	1.22 [0.89, 1.67]
3 Neovascular AMD or geographic atrophy separately	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
3.1 Neovascular AMD	1		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3.2 Geographic atrophy	1		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]