Table 1. Characteristics of patients with mildly symptomatic Mycobacterium avium complex pulmonary disease*.
| Total n = 65 |
Untreated group n = 50 |
Treated group n = 15 |
P value† | |
|---|---|---|---|---|
| Sex | Male 22 | Male 21 | Male 1 | P = 0.011‡ |
| Female 43 | Female 29 | Female 14 | ||
| Age (years) | 65 ± 12.7 | 66 ± 13.5 | 62 ± 9.8 | P = 0.348 |
| Smoking status | ||||
| Current + former smoker | 12 (18.5) | 10 (20.0) | 2 (16.7) | P = 0.559 |
| (Brinkman index) | 447.9 ± 334.6 | 410.0 ± 238.6 | 550.0 ± 226.3 | P = 0.406 |
| Non-smoker | 53 (81.5) | 40 (80.0) | 13 (86.7) | |
| Drinking history | P = 0.245 | |||
| Habitual drinker | 14 (21.5) | 13 (26.0) | 1 (6.7) | |
| Occasional drinker | 7 (10.8) | 5 (10.0) | 2 (13.3) | |
| Non-drinker | 44 (67.7) | 32 (64.0) | 12 (80.0) | |
| Body mass index§ | 21.6 ± 2.5 | 21.7 ± 2.6 | 20.8 ± 2.9 | P = 0.863 |
| %VC (%) || | 89.8 ± 16.0 | 88.5 ± 16.7 | 95.5 ± 12.7 | P = 0.309 |
| %FEV1.0 (%) || | 90.3 ± 26.6 | 91.7 ± 27.1 | 87.6 ± 25.8 | P = 0.500 |
| Peak Flow (l/sec) || | 6.09 ± 1.86 | 6.30 ± 1.91 | 5.30 ± 1.51 | P = 0.176 |
| V50 (l/sec) || | 2.19 ± 1.08 | 2.33 ± 1.08 | 1.68 ± 0.98 | P = 0.133 |
| V25 (l/sec) || | 0.61 ± 0.38 | 0.66 ± 0.38 | 0.44 ± 0.36 | P = 0.161 |
| Radiological findings score (CXR) | ||||
| Nodule | 7 ± 3.9 | 6 ± 3.2 | 11 ± 3.1 | P < 0.001‡ |
| Infiltrate | 3 ± 3.9 | 3 ± 4.1 | 5 ± 2.7 | P = 0.069 |
| Cavity | 0 ± 0.5 | 0 ± 0.5 | 0 ± 0.5 | P = 0.926 |
| Ectasis | 6 ± 3.5 | 5 ± 3.0 | 9 ± 3.4 | P < 0.001‡ |
| Radiological findings score (CT)** | (n = 60) | (n = 47) | (n = 13) | |
| Nodule | 8 ± 4.3 | 8 ± 4.5 | 8 ± 3.7 | P = 0.968 |
| Infiltrate | 3 ± 3.5 | 3 ± 3.7 | 4 ± 2.7 | P = 0.527 |
| Cavity | 0 ± 0.5 | 0 ± 0.5 | 0 ± 0.6 | P = 0.922 |
| Ectasis | 7 ± 4.2 | 7 ± 4.3 | 7 ± 4.1 | P = 0.539 |
%VC, vital capacity as percent of predicted; %FEV1, forced expiratory volume in 1 s as percent of forced vital capacity; V50, flow at 50% of forced vital capacity; V25, flow at 25% of forced vital capacity.
*Data are presented as mean ± SD or n (%).
†: Differences between observation and treatment groups were tested using the χ2 test for categorical data and an unpaired t test for comparison of means.
‡: P < 0.05.
§:BMI at diagnosis are shown. n = 52, 39, 13.
||: Respiratory function test result are shown. n = 38, 30, 8.
**: Radiological findings score on CT are shown. n = 60, 47, 13.