Table 3. Longitudinal changes of clinical features in the treatment group.

	At diagnosis	At start of treatment	Last visit	P value
				Before treatment	After treatment	Throughout observation
Body mass index†	21.5 ± 2.9	20.9 ± 2.7	20.2 ± 2.7	P = 0.626	P = 0.589	P = 0.290
%VC (%)‡	96.6 ± 12.8	95.8 ± 13.3	89.1 ± 14.7	P = 0.922	P = 0.495	P = 0.250
%FEV1 (%)‡	89.7 ± 23.1	82.5 ± 14.3	80.3 ± 24.0	P = 0.125	P = 1.000	P = 0.750
Radiographic scores (CXR) §
Nodule	10.8 ± 3.1	12.1 ± 3.5	11.3 ± 2.9	P = 0.173	P = 0.266	P = 0.636
Infiltrate	5.1 ± 2.7	7.9 ± 4.4	6.9 ± 4.4	P = 0.001*	P = 0.131	P = 0.010*
Cavity	0.1 ± 0.5	0.1 ± 0.5	0.3 ± 0.6	P = 1.000	P = 0.500	P = 0.500
Ectasis	8.9 ± 3.4	10.3 ± 3.0	11.0 ± 3.3	P = 0.049*	P = 0.084	P = 0.016*
Radiographic scores (CT) ||
Nodule	8.3 ± 3.7	12.2 ± 3.7	8.1 ± 4.7	P = 0.014*	P = 0.011*	P = 0.694
Infiltrate	3.6 ± 2.7	5.3 ± 2.6	4.1 ± 2.8	P = 0.007*	P = 0.244	P = 0.730
Cavity	0.2 ± 0.6	0.5 ± 0.9	0.4 ± 0.8	P = 0.593	P = 1.000	P = 0.593
Ectasis	6.5 ± 4.1	9.4 ± 4.9	10.3 ± 4.5	P = 0.109	P = 0.603	P = 0.028*

%VC, vital capacity as percent of predicted; %FEV₁, Forced expiratory volume in 1 second as percent of forced vital capacity

Patients without follow-up pulmonary function testing were excluded.

*t test (p < 0.05).

†:BMI at diagnosis are shown. n = 13, 9, 10.

‡: Respiratory function test result are shown. n = 8, 5, 4.

§: Radiological findings score on CXR are shown. n = 15, 15, 15.

||: Radiological findings score on CT are shown. n = 13, 13, 13.