Table 4. Comparison of bacterial factors at diagnosis between the observation and treatment groups.
| Total n = 65 (%) |
Untreated group n = 50 (%) |
Treated group n = 15 (%) |
P value | |
|---|---|---|---|---|
| Isolated species | ||||
| M.avium | 59 (90.8) | 44 (88.0) | 15 (100.0) | P = 0.060 |
| M.intracellulare | 6 (9.2) | 4 (8.0) | 2 (13.3) | P = 0.531 |
| M.fortuitum | 3 (4.6) | 1 (2.0) | 2 (13.3) | P = 0.187 |
| M.abscessus | 4 (6.2) | 4 (8.0) | 0 (0.0) | P = 0.331 |
| MAC | 3 (4.6) | 3 (6.0) | 0 (0.0) | P = 0.331 |
| Polyclonality analyzed by VNTR | ||||
| Polyclonal + mixed infection | 15 (23.1) | 9 (18.0) | 6 (40.0) | P = 0.076 |
| Polyclonal infection | 9 (13.8) | 4 (8.0) | 5 (33.3) | P = 0.013* |
| Mixed infection | 10 (15.3) | 6 (12.0) | 4 (26.7) | P = 0.167 |
| Insertion sequence† | (n = 55) | (n = 40) | (n = 15) | |
| IS 1245 | 49 (89.1) | 36 (90.0) | 13 (86.7) | P = 0.724 |
| IS 1311 | 44 (80.0) | 31 (77.5) | 13 (86.7) | P = 0.449 |
| IS Mav6 | 29 (52.7) | 19 (47.5) | 10 (66.7) | P = 0.205 |
| IS Mav6 in Cfp29 region | 13 (23.6) | 11 (27.5) | 2 (13.3) | P = 0.271 |
| Plasmids † | (n = 53) | (n = 39) | (n = 14) | |
| pMAH | 9 (17.0) | 6 (15.3) | 3 (21.4) | P = 0.605 |
| pLR7 | 1 (1.9) | 1 (2.6) | 0 (0.0) | P = 0.545 |
| pVT2 | 10 (18.9) | 6 (15.4) | 4 (28.6) | P = 0.279 |
| pMAH + pVT2 | 5 (9.4) | 3 (7.7) | 2 (14.3) | P = 0.469 |
| pMAH + pLR7 + pVT2 | 0 (0.0) | 0 (0.0) | 0 (0.0) |
VNTR, variable-number tandem-repeat.
*P < 0.05.
†: Only cases in which we could isolate and evaluate the strains of Mycobacterium avium.