Table 2. Clinical aspects of patients with paracoccidioidomycosis according to the species identified in this study.
| Variable analyzed | P. brasiliensis (n = 41) | P. americana (n = 6) | p value* | ||
|---|---|---|---|---|---|
| n | % (95% CI) | n | % (95% CI) | ||
| Clinical form | |||||
| Chronic | 23 | 56 (41–71) | 5 | 83 (54–100) | 0.3783 |
| Acute/subacute | 16 | 39 (24–54) | 1 | 17 (0–46) | 0.3958 |
| Mixed | 2 | 5 (0–11) | 0 | 0 | 1.0000 |
| Severity | |||||
| Mild | 7 | 17 (6–29) | 1 | 17 (0–46) | 1.0000 |
| Moderate | 18 | 44 (29–59) | 4 | 67 (29–100) | 0.3980 |
| Severe | 16 | 39 (24–54) | 1 | 17 (0–46) | 0.3958 |
| Organs affected | |||||
| UAWT | 26 | 63 (49–78) | 5 | 83 (54–100) | 0.6484 |
| Larynx | 7 | 17 (6–29) | 2 | 33 (0–71) | 0.3222 |
| Lungs | 23 | 56 (41–71) | 5 | 83 (54–100) | 0.3783 |
| Lymph nodes | 21 | 51 (36–67) | 2 | 33 (0–71) | 0.6662 |
| Skin | 16 | 39 (24–54) | 0 | 0 | 0.0819 |
| Liver/spleen | 10 | 24 (11–38) | 0 | 0 | 0.3173 |
| Adrenal | 6 | 14 (6–29) | 3 | 50 (12–88) | 0.0747 |
| Bone marrow | 3 | 7 (0–15) | 0 | 0 | 1.0000 |
| CNS | 2 | 5 (0–11) | 0 | 0 | 1.0000 |
| Bone | 2 | 5 (0–11) | 0 | 0 | 1.0000 |
| Coinfections | |||||
| Tuberculosis | 3 | 7 (0–15) | 0 | 0 | 1.0000 |
| HIV/AIDS | 5 | 12 (4–26) | 0 | 0 | 1.0000 |
| Viral hepatitis | 2 | 5 (0–11) | 1 | 17 (0–46) | 0.3426 |
| Intestinal worms | 6 | 14 (6–29) | 2 | 33 (0–71) | 0.2672 |
CI–confidence interval; UAWT–upper airway tract; CNS–central nervous system
* p value based on Fisher’s exact test