Table 3. Therapeutic aspects of patients with paracoccidioidomycosis according to the species identified in this study.
| Drug prescribed | P. brasiliensis (n = 41) | P. americana (n = 6) | p valuea | ||
|---|---|---|---|---|---|
| n | mean time (months) | n | mean time (months) | ||
| ITZ | 12 | 15.7 | 1 | 15 | NCb |
| SMZ/TMP | 6 | 19.3 | 2 | 27.5 | 0.4841 |
| ITZ and SMZ/TMPc | 10 | 20.7 | 3 | 18.6 | 0.8304 |
| Othersd | 12 | 44.2 | 0 | - | NC |
ITZ–itraconazole; SMZ/TMP–sulfamethoxazole-trimethoprim
a p value based on Student’s t test
b NC–Not calculated due to small sample size in P. americana group.
c Sequentially prescribed due to adverse effects or refractoriness
d Drug combinations and amphotericin B