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. 2017 Aug 4;2017(8):CD005494. doi: 10.1002/14651858.CD005494.pub4

Soliz 2009.

Methods Randomised clinical trial
Participants 49 term neonates with PPHN and OI > 25 were included
Interventions Randomised to placebo (n = 20) vs sildenafil (n = 29)
Outcomes OI, mean blood pressure and mean airway pressure
Notes Difficult to differentiate from included studies, as some study authors overlap

FiO2 = fraction of inspired oxygen
 GA = gestational age
 MAS = meconium aspiration syndrome
 MPA = mean pulmonary artery
 MPAP = mean pulmonary arterial pressure
 NICU = neonatal intensive care unit
 OI = oxygenation index
 PO2 = partial pressure of oxygen
 PPHN = persistent pulmonary hypertension in the neonate
 RVEDD = right ventricular end‐diastolic diameter
 SD = standard deviation
 SpO2 = peripheral capillary oxygen saturation
 TR = tricuspid regurgitation