Soliz 2009.
Methods | Randomised clinical trial |
Participants | 49 term neonates with PPHN and OI > 25 were included |
Interventions | Randomised to placebo (n = 20) vs sildenafil (n = 29) |
Outcomes | OI, mean blood pressure and mean airway pressure |
Notes | Difficult to differentiate from included studies, as some study authors overlap |
FiO2 = fraction of inspired oxygen GA = gestational age MAS = meconium aspiration syndrome MPA = mean pulmonary artery MPAP = mean pulmonary arterial pressure NICU = neonatal intensive care unit OI = oxygenation index PO2 = partial pressure of oxygen PPHN = persistent pulmonary hypertension in the neonate RVEDD = right ventricular end‐diastolic diameter SD = standard deviation SpO2 = peripheral capillary oxygen saturation TR = tricuspid regurgitation