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. 2017 Jul 7;2017(7):CD010810. doi: 10.1002/14651858.CD010810.pub3
Term Definition
Complement‐dependent cytotoxicity (CDC) Binding of the antibody recruits complement proteins, which punch holes in the cell membrane, flooding the cell and leading to celllysis.
Apoptosis Binding of the antibody signals the cell to self‐destruct.
Antibody‐dependent cell‐mediated cytotoxicity (ADCC) Natural killer cells, T cells, and macrophages are involved in recognizing and killing antibody‐labelled target cells, leading to celllysis.