Term | Definition |
Complement‐dependent cytotoxicity (CDC) | Binding of the antibody recruits complement proteins, which punch holes in the cell membrane, flooding the cell and leading to celllysis. |
Apoptosis | Binding of the antibody signals the cell to self‐destruct. |
Antibody‐dependent cell‐mediated cytotoxicity (ADCC) | Natural killer cells, T cells, and macrophages are involved in recognizing and killing antibody‐labelled target cells, leading to celllysis. |