| Trial name or title | SURV1VE‐Trial ‐ Sustained inflation and chest compression versus 3:1 chest compression to ventilation ratio during cardiopulmonary resuscitation of asphyxiated newborns: a randomised controlled trial |
| Methods | Prospective randomised parallel controlled trial |
| Participants | Infants (term or preterm infants) requiring chest compressions in the delivery room |
| Interventions | SLI group: PIP of 25 to 30 cmH2O for 45 seconds while receiving chest compression. This will be followed by PEEP of 5 to 8 cmH2O. If heart rate < 60/min, continue with chest compression + SLI for another 45 seconds. If heart rate remains < 60/min, continue with CC + SI Control group: chest compression at a rate of 90/min and 30 ventilations/min in a 3:1 C:V ratio |
| Outcomes | Primary outcomes: return of spontaneous circulation; duration of chest compression heart rate is > 60/min for 15 seconds |
| Starting date | January 2017 |
| Contact information | Georg Schmolzer, MD, PhD; georg.schmoelzer@me.com University of Alberta |
| Notes | Estimated enrolment: 118 Estimated primary completion date: December 2018 |
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