| Trial name or title | The effect of sustained lung inflation maneuver applied through nasal prong on early and late respiratory morbidities in preterm infants |
| Methods | Prospective randomised parallel controlled trial |
| Participants | Preterm infants of 26 weeks 0 days and 29 weeks 6 days |
| Interventions | SLI group: PIP 25 cmH2O for 15 seconds with T‐piece and bi‐nasal prongs; second SLI in case of poor response Control group: CPAP |
| Outcomes | Primary outcome: surfactant need, intubation and mechanical ventilation needs within first 72 hours of life Secondary outcomes: heart rate, fractional inspiratory oxygen, CPAP pressure and oxygen saturation within first 72 hours of life in preterm infants; total non‐invasive, invasive respiratory support time; BPD; PDA; IVH, NEC; ROP; feeding intolerance, reaching birth weight; transition to full oral feeding time |
| Starting date | August 2016 |
| Contact information | Zekai Tahir Burak Women's Health Research and Education Hospital, Ankara, Turkey |
| Notes | Estimated enrolment: 250 Estimated primary completion date: September 2017 |
BPD: bronchopulmonary dysplasia CC: chest compression C:V: compression: ventilation CPAP: continuous positive airway pressure DR: delivery room FiO2: fraction of inspired oxygen IVH: intraventricular haemorrhage NICU: neonatal intensive care unit PEEP: positive end‐expiratory pressure PIE: pulmonary interstitial emphysema PIP: peak inspiratory pressure PPV: positive pressure ventilation ROP: retinopathy of prematurity SI: sustained inflation SLI: sustained lung inflation