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. 2017 Jul 26;2017(7):CD001754. doi: 10.1002/14651858.CD001754.pub4
Methods RCT (block‐randomisation technique). Follow‐up reported at 6 months. Selection criteria were well reported
Participants 75 women with mixed incontinence symptoms and a negative cystometrogram for motor detrusor overactivity. All had proven stress urinary incontinence. No details on demographic data were reported
21 participants (anticholinergic) and 24 (sling) were available to follow up
Interventions A (50): surgery (Ai (24) Burch colposuspension, Aii (26) rectus fascia sling)
B (25): anticholinergic treatment
Outcomes Participants were evaluated by SEAPI score (subjective and objective) and underwent urodynamic examination pre and post treatment
Cure for urge symptoms: Aii: 88%; B:57%
Cure for SUI: Aii: 83%; B: 0
Notes The study was designed to investigate anticholinergic therapy in comparison with surgery. Participants allocated to surgery had a sling procedure if the Valsalva leak point pressure was < 90 cm H2O. We extracted only data on sling in comparison with anticholinergics
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Block randomisation
Allocation concealment (selection bias) Unclear risk Not mentioned
Blinding (performance bias and detection bias) All outcomes Unclear risk Not mentioned
Incomplete outcome data (attrition bias) All outcomes Low risk Of 75 women randomised, 68 evaluated at 6 months. Four lost in anticholinergic arm and 3 in surgical arm. Insufficient information to determine whether appropriately addressed or not