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. 2017 Aug 8;2017(8):CD006008. doi: 10.1002/14651858.CD006008.pub4
Methods DESIGN: Randomised controlled trial BLINDING PROCEDURES: Double blind SAMPLE CALCULATION: Yes DURATION: 4 weeks WITHDRAWALS/DROPOUTS: Unclear ITT: Yes and also per protocol analysis GEOGRAPHICAL LOCATION: 6 European countries (13 centres) SETTING: Community
Participants N = 195 DIAGNOSIS: Mixed ELIGIBLE: Not stated ENROLLED: 195 COMPLETED: Unclear AGE: Adults GENDER: 151 male; 44 female
Interventions Hydrophilic‐coated catheter, not activated, sterile water provided versus hydrophilic‐coated catheter, not activated, water added by user (aseptic technique both arms)
Outcomes Participant perception of handling
Notes Participant perception of handling was rated similarly in both groups
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not stated
Allocation concealment (selection bias) Unclear risk Not stated
Blinding of participants and personnel (performance bias) All outcomes Low risk "Since most polymeric materials are visually similar, comparable materials could be produced and packaged in identical form".
This was set up as a double‐blind trial.
Blinding of outcome assessment (detection bias) All outcomes Low risk This was set up as a double‐blind trial.
Incomplete outcome data (attrition bias) All outcomes Low risk Similar incomplete outcome data in control (n = 6) and intervention (n = 10) groups
Source of Funding Unclear risk Not stated

BPH: benign prostatic hyperplasia CFU/mL: colony‐forming unit per millilitre CIC: Clean Intermittent Catheterization C&S: culture and sensitivity IC: intermittent catheterisation ICU: intensive care unit ISC‐Q: Intermittent Self‐Catheterisation Questionnaire ITT: intention‐to‐treat NIDRR: National Institute on Disability and Rehabilitation Research RBC per HPF: red blood cell per RCT: randomised controlled trial SS: UI: urinary infection UTI: urinary tract infection VAS: visual analogue scale