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. 2012 Nov 14;2012(11):CD007407. doi: 10.1002/14651858.CD007407.pub3

Wetherell 2011.

Methods RCT; 2 arms; acceptance and commitment therapy, CBT; post‐treatment and 6 month follow‐up
Participants End of treatment: n = 99
Start of treatment: n = 114
Sex: 58 F; 56 M
Mean age: 54.9 (SD 12.5)
Mean years of pain: 15 (SD 35.5)
Source = primary care (40%); adverts and newspaper article (40%); pain support groups (10%); various (10%)
Diagnosis = mixed chronic pain
Interventions ACT versus CBT
Outcomes Primary pain outcome: BPI pain severity
Primary disability outcome: BPI interference
Primary mood outcome: BDI
Catastrophising outcome: none
Pain severity: BPI Sub‐scale
Disability: BPI Interference Sub‐scale (primary outcome)
Disability: MPI General Activity Sub‐scale
Depression: BDI‐II
Anxiety: PASS
Quality of life: SF‐12 physical and mental subscores
Treatment Satisfaction Questionnaire
Notes ACT versus CBT: analyses 1.1, 1.2, 1.3, 2.1, 2.2, 2.3
2011 update search.
Yates quality scale: total quality = 32/35, design quality = 24/26, treatment quality = 8/9
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Group randomisation generated by computer
Allocation concealment (selection bias) Low risk Staff member who accessed randomisation code had no contact with participants
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Attrition fully reported; several differences between dropouts and completers
Selective reporting (reporting bias) Low risk Fully reported
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Assessment staff blind to treatment condition