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. 2017 Jul 31;2017(7):CD006375. doi: 10.1002/14651858.CD006375.pub4

Nerli 2009.

Methods QRCT of TVT vs TOT
Participants Inclusion criteria: women > 18 years; with SUI or MUI if SUI is the predominant symptom; women with ISD
Exclusion criteria: predominant urge incontinence; UTI; malignancy; pregnancy; POP stage 3 or 4
Mean age (years; SD): Group A: 39.5 (1.95); Group B: 50.2 (1.89)
Post menopausal status: Group A 8/18; Group B: 6/18
Interventions Group A: TVT (n = 18)
Group B: TOT (n = 18)
Outcomes
  • Objective cure: negative cough stress test

  • Subjective cure: self‐reported absence of SUI

  • Improved: persistence of SUI not affecting daily activity or requiring further treatment plus negative cough test

  • Mean operative time

  • Mean operative blood loss

  • Voiding dysfunction

  • Bladder perforation

  • De novo urge incontinence

  • Tape erosion

  • Days to return to normal activity

Notes Cystoscopy performed only in the TVT group
I‐QOL questionnaire assessed at 12 month F/U: significant improvement in I‐QOL total scores in both groups from the pre‐operative baseline scores.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk Allocation of participants by alternation (quasi randomised)
Allocation concealment (selection bias) High risk Allocation not concealed
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk No information
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk No information
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk No information