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. 2017 Jul 28;2017(7):CD007807. doi: 10.1002/14651858.CD007807.pub3
Methods Randomised trial
Participants Women undergoing IVF aged 22 ‐ 43 years. Mean age treatment group: 30.7 ± 4.5; placebo group: 28.8 ± 3.2) (n = 56)
Inclusion criteria: non‐smokers, free from major illness including hypertension, all interested in becoming pregnant
Exclusion criteria: myoma, adenomyosis, congenital abnormality, ovarian tumours, hormone or long‐term medication use
Interventions 1. Multi‐vitamin/mineral (containing vitamins A, B, C, D, E and H, calcium, folic acid, nicotinic acid, iron, magnesium, phosphor copper, manganese and zinc): 1 tablet a day (n = 26)
2. Placebo (candy) (n = 30).
for 45 days
Outcomes Follicular fluid
Notes Conducted in Turkey
3 groups were used in the study. The 1st group consisted of age‐matched controls, so we did not use these data in this review. The 2nd and 3rd groups were randomly assigned
Author emailed on 1st August 2012 to ask for any data on pregnancy, live birth or adverse events. Author replied on 13th August 2012. No outcomes appropriate to this review.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Randomised by a computer‐generated list
Allocation concealment (selection bias) Unclear risk Not mentioned
Blinding (performance bias and detection bias) All outcomes High risk Placebo used was candy
Incomplete outcome data (attrition bias) All outcomes Unclear risk None mentioned
Selective reporting (reporting bias) Low risk None known
Other bias Low risk No other bias found