Methods | Prospective, randomized, double‐blind placebo‐controlled trial | |
Participants | Infertile women undergoing IVF/ICSI, 34 women with ICSI cycles and 18 oocyte donation (n = 52) | |
Interventions | 1. Vitamin D 100.000 IU: 1 tablet per month (n = 26) 2. Placebo (n = 26) Trial duration; 5 consecutive months |
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Outcomes | Endometrial thickness Number of oocytes retrieved Cancellation rate Number of embryos transferred Implantation rate Clinical pregnancy rate Live birth |
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Notes | Conducted in Argentina,study dates not reported conference abstract Funding source not reported Author email; ester_polak@cermed.com. Author contacted on the 20th November 2015 regarding risk of bias factors and live birth data. Author replied 14th December 2015 regarding dropouts, miscarriage, adverse effects and live birth. Trial not yet published as a full text |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | "Fifty two patients were computer randomized" |
Allocation concealment (selection bias) | Unclear risk | Unknown |
Blinding (performance bias and detection bias) All outcomes | Low risk | "Double blind" (placebo control) |
Incomplete outcome data (attrition bias) All outcomes | Low risk | "no dropouts" email from author |
Selective reporting (reporting bias) | Low risk | No known selective reporting |
Other bias | Low risk | No other bias found |