Foletto 2014.
| Methods |
Study design: randomized, controlled trial Sample‐size calculation: No information available |
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| Participants |
Number of randomized patients: 34 morbidly obese (MO) patients Inclusion criteria: morbidly obese and undergoing laparoscopic‐sleeve gastrectomy Exclusion criteria: no information available |
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| Interventions |
Anaesthesia: propofol and remifentanil anaesthesia; no further information available NMBA: rocuronium; no further information available Comparison: sugammadex 2 mg/kg (n = 17) vs neostigmine 50 µg/kg (n = 17) Administration time of sugammadex or neostigmine: reappearance of T1 to 2 |
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| Outcomes | Recovery time to TOFR > 0.9, spirometry 15 minutes postoperative (postoperative forced vital capacity, forced expiratory volume in 1 second, peak expiratory flow) | |
| Notes |
Publication type: meeting abstract Country: Italy Conversions: none Authors’ conclusions: Respiratory function was restored more quickly in morbidly obese participants who received sugammadex to reverse rocuronium‐induced NMB Contact: first trial author Mirto Foletto contacted by email: mirto.foletto@unipd.it on 07.10.2015; no reply received |
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| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | "Random"; no further information |
| Allocation concealment (selection bias) | Unclear risk | Unable to assess owing to insufficient information |
| Blinding of participants (performance bias) | Unclear risk | Unable to assess owing to insufficient information |
| Blinding of personnel (performance bias) | Unclear risk | Unable to assess owing to insufficient information |
| Blinding of primary outcome assessment (detection bias) | Unclear risk | Unable to assess owing to insufficient information |
| Blinding of safety assessment (detection bias) | Unclear risk | Unable to assess owing to insufficient information |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Unable to assess owing to insufficient information |
| Selective reporting (reporting bias) | Unclear risk | Unable to assess owing to insufficient information |
| Funding bias | Unclear risk | Unable to assess owing to insufficient information |
| Other bias | Unclear risk | No differences in participant characteristics, anaesthetic drugs, and baseline spirometry were observed between groups. No information on sample size calculation was provided |