Sherman 2014.
Methods |
Study design: prospective, randomized study Sample size calculation: no information available |
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Participants |
Number of randomized participants: 57 Inclusion criteria: undergoing laparoscopic sleeve gastrectomy Exclusion criteria: no information available |
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Interventions |
Anaesthesia: no information available NMBA: no information available Comparison: sugammadex 2 mg/kg (n = 32) vs neostigmine 2.5 mg (n = 25) Administration time of sugammadex or neostigmine: completion of surgery |
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Outcomes | Postoperative complications: critical respiratory events, pulmonary complications, minimum SpO2 values in the PACU, airway and pulmonary morbidity, unexpected ICU admission, incidence of reintubation, and duration of hospitalizations | |
Notes |
Publication type: meeting abstract Country: Israel Conversions: none Authors’ conclusions: Use of sugammadex (compared with neostigmine) as a reversal agent following laparoscopic sleeve gastrectomy surgery was associated with higher postoperative oxygen saturation despite lower TOF count before administration of reversal agent. Lack of differences in other measured variables may stem from the small patient groups studied Contact: first trial author Tiberiu Ezri contacted by email: tezri@netvision.net.il on 26.05.2016; no reply received |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "Randomized study"; no further information available |
Allocation concealment (selection bias) | Unclear risk | Unable to assess owing to insufficient information |
Blinding of participants (performance bias) | Unclear risk | Unable to assess owing to insufficient information |
Blinding of personnel (performance bias) | Unclear risk | Unable to assess owing to insufficient information |
Blinding of primary outcome assessment (detection bias) | Unclear risk | Unable to assess owing to insufficient information |
Blinding of safety assessment (detection bias) | Unclear risk | Unable to assess owing to insufficient information |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Unable to assess owing to insufficient information |
Selective reporting (reporting bias) | Low risk | Study protocol not available, but published meeting abstract clearly includes all expected outcomes |
Funding bias | Unclear risk | Unable to assess owing to insufficient information |
Other bias | Unclear risk | Unable to assess owing to insufficient information. Demographic data were similar between groups |