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. 2017 Aug 14;2017(8):CD012763. doi: 10.1002/14651858.CD012763

Sherman 2014.

Methods Study design: prospective, randomized study
Sample size calculation: no information available
Participants Number of randomized participants: 57
Inclusion criteria: undergoing laparoscopic sleeve gastrectomy
Exclusion criteria: no information available
Interventions Anaesthesia: no information available
NMBA: no information available
Comparison: sugammadex 2 mg/kg (n = 32) vs neostigmine 2.5 mg (n = 25)
Administration time of sugammadex or neostigmine: completion of surgery
Outcomes Postoperative complications: critical respiratory events, pulmonary complications, minimum SpO2 values in the PACU, airway and pulmonary morbidity, unexpected ICU admission, incidence of reintubation, and duration of hospitalizations
Notes Publication type: meeting abstract
Country: Israel
Conversions: none
Authors’ conclusions: Use of sugammadex (compared with neostigmine) as a reversal agent following laparoscopic sleeve gastrectomy surgery was associated with higher postoperative oxygen saturation despite lower TOF count before administration of reversal agent.
Lack of differences in other measured variables may stem from the small patient groups studied
Contact: first trial author Tiberiu Ezri contacted by email: tezri@netvision.net.il on 26.05.2016; no reply received
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "Randomized study"; no further information available
Allocation concealment (selection bias) Unclear risk Unable to assess owing to insufficient information
Blinding of participants (performance bias) Unclear risk Unable to assess owing to insufficient information
Blinding of personnel (performance bias) Unclear risk Unable to assess owing to insufficient information
Blinding of primary outcome assessment (detection bias) Unclear risk Unable to assess owing to insufficient information
Blinding of safety assessment (detection bias) Unclear risk Unable to assess owing to insufficient information
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Unable to assess owing to insufficient information
Selective reporting (reporting bias) Low risk Study protocol not available, but published meeting abstract clearly includes all expected outcomes
Funding bias Unclear risk Unable to assess owing to insufficient information
Other bias Unclear risk Unable to assess owing to insufficient information. Demographic data were similar between groups