Sustic 2012.

Methods	Study design: prospective, randomized clinical study Sample size calculation: no information available
Participants	Number of randomized participants: 42 Inclusion criteria: adults undergoing laparoscopic cholecystectomy Exclusion criteria: no information available
Interventions	Anaesthesia: no information available NMBA: single intubating dose: rocuronium 0.6 mg/kg; maintenance dose: rocuronium 0.15 to 3 mg/kg Comparison: sugammadex 2 mg/kg (n = 21) vs neostigmine 40 µg/kg + atropine group 15 µg/kg (n = 21) Administration time of sugammadex or neostigmine: no information available
Outcomes	Gastric emptying evaluated by paracetamol absorption test. Paracetamol absorption was assessed from the plasma paracetamol concentration (PPC)
Notes	Publication type: meeting abstract Country: Croatia Conversions: none Authors’ conclusions: Although study results show a tendency toward faster gastric emptying in the sugammadex group, this difference is not significant in most, possibly owing to small sample size Contact: first author Alan Sustic contacted by email: alan.sustic@uniri.hr on 24.05.2016; replied 25.05 * Indicates unpublished data
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer randomization *
Allocation concealment (selection bias)	Unclear risk	Unable to assess owing to insufficient information
Blinding of participants (performance bias)	High risk	Participants not blinded *
Blinding of personnel (performance bias)	High risk	Participants not blinded *
Blinding of primary outcome assessment (detection bias)	Low risk	Not relevant as TOF measurement not performed in this study
Blinding of safety assessment (detection bias)	Low risk	Outcomes assessor was blinded *
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Unable to assess owing to insufficient information
Selective reporting (reporting bias)	Low risk	Study protocol not available, but published meeting abstract clearly includes all expected outcomes
Funding bias	Unclear risk	Unable to assess owing to insufficient information
Other bias	Unclear risk	Unable to assess owing to insufficient information