NCT03144453.

Trial name or title	Recovery from anesthesia after robotic assisted radical cystectomy
Methods	Allocation: randomized Intervention model: parallel assignment Masking: participant, care provider, investigator, outcomes assessor Primary purpose: treatment
Participants	Estimated enrolment: 50 Inclusion criteria: ≥ 18 years of age ASA score ≤ III Underwent robotic assisted cystectomy Exclusion criteria: Cerebrovascular disease BMI (body mass index) ≥ 30
Interventions	Control group: Participants received neostigmine + atropine as neuromuscular blockade reversal Interventions group: Participants received sugammadex as neuromuscular blockade reversal
Outcomes	Primary outcome measures: Time to discharge from recovery room [Time Frame: up to 240 minutes after recovery] Time between reversal administration and discharge from recovery room
Starting date	2 May 2017
Contact information	Ester Forastierem Rome, Italy Contact: Ester Forastiere: ester.forastiere@ifo.gov.it Regina Elena Cancer Institute, Rome,Italy Contact: Forastiere Ester: forastiere@ifo.it Sub‐Investigator: Claudia Claroni
Notes	Currently recruiting participants. Estimated Study Completion Date: November 2017

List of acronyms and abbreviations used in these tables

ASA ‐ American Society of Anesthesiology; BMI ‐ body mass index; CI ‐ confidence interval; CNS ‐ central nervous system; COPD ‐ chronic obstructive pulmonary disease; CrCL ‐ creatinine clearance; DEF – dynamic end‐tidal forcing; DL – diffusion lung capacity; DLCO/VA – diffusion lung capacity for carbon monoxide/alveolar volume ratio; dNMB – deep neuromuscular blockage; eGFR ‐ estimated glomerular filtration rate;

ENT – ear, nose, and throat; FEV₁ – forced expiratory volume in one second; FiO₂ ‐ fraction of inspired oxygen; FVC – functional vital capacity; GCS – Glasgow Coma Scale; GOLD – Global initiative for Chronic Obstructive Lung Disease; Hb ‐ haemoglobin; IU/L – international unit/litre; ICU ‐ intensive care unit; IU/L ‐ international units/litre; IV ‐ intravenous; MedDRA ‐ Medical Dictionary for Regulatory Activities; MELD ‐ model for end‐stage liver disease; METS ‐ metabolic equivalent of tasks; NMB ‐ neuromuscular blocking; NMBA ‐ neuromuscular blocking agent; NSQIP ‐ national surgical quality improvement program; OR ‐ operations room; PaCO2 ‐ partial pressure of carbon dioxide; PACU ‐ post anaesthesia care unit; PADSS ‐ post anaesthesia discharge score system; PaO₂ ‐ partial pressure of oxygen in blood; PEF ‐ peak expiratory flow; pO₂ ‐ partial pressure of oxygen; PONV ‐ postoperative nausea and vomiting; PTC ‐ post‐tetanic count; PQRS ‐ postoperative quality recovery scale; SpO₂ ‐ peripheral oxygen saturation; Sq ‐ square; SRS ‐ surgical rating score; TOF ‐ train of four; TOFR ‐ train‐of‐four ratio; VA ‐ alveolar volume; VAS ‐ visual analogue scale