Comparison 3. IB 40 vs IB 80.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Symptom score (scale ‐4 to +4)	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
1.1 Dyspnoea daytime	1	26	Mean Difference (IV, Fixed, 95% CI)	‐0.30 [‐0.85, 0.25]
1.2 Cough daytime	1	26	Mean Difference (IV, Fixed, 95% CI)	‐0.50 [‐1.12, 0.12]
1.3 Dyspnoea night	1	26	Mean Difference (IV, Fixed, 95% CI)	‐0.20 [‐0.91, 0.51]
2 PEF (scale ‐100 to +100 l/min)	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
2.1 PEF am	1	26	Mean Difference (IV, Fixed, 95% CI)	34.0 [‐4.06, 72.06]
2.2 PEF pm	1	26	Mean Difference (IV, Fixed, 95% CI)	24.0 [‐19.16, 67.16]
2.3 PEF post dose, am	1	26	Mean Difference (IV, Fixed, 95% CI)	29.00 [‐11.21, 69.21]