| 1 Tranquillisation or asleep ‐ asleep |
1 |
39 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.93 [1.04, 3.60] |
| 1.1 not asleep up to 2 hours |
1 |
39 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.93 [1.04, 3.60] |
| 2 Repeated need for rapid tranquillisation |
1 |
|
Risk Ratio (M‐H, Fixed, 95% CI) |
Subtotals only |
| 2.1 more that 1 injection |
1 |
30 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.07 [0.89, 1.28] |
| 2.2 more than 3 injections |
1 |
30 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.5 [0.53, 4.26] |
| 3 Global outcome: 1. Not improved |
2 |
|
Risk Ratio (M‐H, Fixed, 95% CI) |
Subtotals only |
| 3.1 not marked improvement |
2 |
89 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.79 [0.61, 1.02] |
| 3.2 not any improvement |
2 |
89 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.15 [0.05, 0.49] |
| 4 Adverse effects: any serious or specific adverse effects |
3 |
|
Risk Ratio (M‐H, Fixed, 95% CI) |
Subtotals only |
| 4.1 allergy ‐ haematological ‐ leucopenia ‐ mild |
1 |
50 |
Risk Ratio (M‐H, Fixed, 95% CI) |
3.0 [0.13, 70.30] |
| 4.2 allergy ‐ hepatic ‐ glutamic pyruvic transaminase elevated |
1 |
50 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.33 [0.01, 7.81] |
| 4.3 allergy ‐ skin irritation ‐ local |
1 |
30 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 4.4 anticholinergic ‐ dry mouth |
1 |
39 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.38 [0.17, 10.93] |
| 4.5 arousal ‐ drowsy but asleep |
1 |
39 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.06 [0.01, 0.42] |
| 4.6 arousal ‐ drowsy but awake |
1 |
39 |
Risk Ratio (M‐H, Fixed, 95% CI) |
9.17 [0.59, 142.10] |
| 4.7 cardiovascular ‐ hypotension |
2 |
69 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.51 [0.10, 2.60] |
| 4.8 central nervous system ‐ seizures |
1 |
30 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.33 [0.01, 7.58] |
| 4.9 movement disorders ‐ extrapyramidal adverse effects |
2 |
69 |
Risk Ratio (M‐H, Fixed, 95% CI) |
2.07 [0.28, 15.15] |
| 5 Leaving the study early |
4 |
|
Risk Ratio (M‐H, Fixed, 95% CI) |
Subtotals only |
| 5.1 any reason/general reasons |
4 |
153 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.21 [0.07, 0.71] |
| 5.2 could not be evaluated due to being asleep |
1 |
39 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.07 [0.01, 0.52] |
| 5.3 severe hypotensive reaction |
1 |
30 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.2 [0.01, 3.85] |
| 5.4 deviation from protocol |
1 |
30 |
Risk Ratio (M‐H, Fixed, 95% CI) |
3.0 [0.13, 68.26] |
