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. 2017 Jul 31;2017(7):CD009377. doi: 10.1002/14651858.CD009377.pub3

Comparison 21. HALOPERIDOL vs COMBINATIONS: f. OLANZAPINE + MAGNESIUM VALPROATE.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Specific behaviour: 1. Agitation ‐ average scores ‐ over 24 hours 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.1 endpoint score at 72 hours (PANSS‐EC, high=worse) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
1.2 endpoint score at 7 days (PANSS‐EC, high=worse) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
1.3 endpoint score at 14 days (PANSS‐EC, high=worse) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
2 Global outcome: No improvement 1 64 Risk Ratio (M‐H, Fixed, 95% CI) 1.06 [0.38, 2.95]
3 Mental state: Average scores ‐ i. over 24 hours 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
3.1 endpoint score at 72 hours (PANSS total, high=worse) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.2 endpoint score at 7 days (PANSS total, high=worse) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.3 endpoint score at 14 days (PANSS total, high=worse) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
4 Adverse effects: General ‐ over 24 hours 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
4.1 one or more drug related adverse effects ‐ by 14 days 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]