Date	Event	Description
3 July 2014	New search has been performed	One new trial has been included in the review update (Avis 2010). We are now using the definitions of statin‐related myopathy provided by the U.S. Food and Drug Administration which relate to two clinical entities are used: (1) myopathy (creatine kinase over 10 x ULN); and (2) rhabdomyolysis (creatine kinase over 50 ULN and evidence of organ damage) (Joy 2009). One sub‐study of the de Jongh 2002 study (de Jongh 2002b), previously listed as a separate included study, has been correctly linked under the de Jongh 2002 included study (de Jongh 2002a).
3 July 2014	New citation required but conclusions have not changed	One new trial has been included in this update of the review (Avis 2010). However, this did not lead to any major changes in the conclusions of the review.
20 October 2008	Amended	Converted to new review format.
15 October 2007	New citation required and conclusions have changed	Substantive amendment