Comparison 1. Risperidone versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Aggression: ABC irritability (mean change scores)	3	238	Mean Difference (IV, Random, 95% CI)	‐6.49 [‐8.79, ‐4.19]
2 Aggression: OAS‐M, ABS Reactive subscale (final scores)	2	190	Mean Difference (IV, Random, 95% CI)	‐1.30 [‐2.21, ‐0.40]
3 Aggression: OAS‐M, ABS Proactive subscale (final scores)	2	190	Mean Difference (IV, Random, 95% CI)	‐1.12 [‐2.30, 0.06]
4 Conduct: NCBR‐CP (mean change scores)	2	225	Mean Difference (IV, Random, 95% CI)	‐8.61 [‐11.49, ‐5.74]
5 Weight gain (antipsychotic only): Kg (mean change scores)	2	138	Mean Difference (IV, Random, 95% CI)	2.37 [0.26, 4.49]
6 Weight gain (antipsychotic and stimulant): Kg (mean change scores)	3	305	Mean Difference (IV, Random, 95% CI)	2.14 [1.04, 3.23]