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. 2017 Aug 11;2017(8):CD007776. doi: 10.1002/14651858.CD007776.pub3

Summary of findings for the main comparison. Preconception care versus standard care for diabetic women: outcomes for the woman.

Preconception care versus standard care for diabetic women for improving maternal and infant health: women's outcomes
Patient or population: adolescent girls with type 1 or type 2 diabetes
 Setting: USA
 Intervention: preconception care
 Comparison: standard care
Outcomes Anticipated absolute effects* (95% CI) Relative effect
 (95% CI) № of participants
 (studies) Quality of the evidence
 (GRADE) Comments
Risk with standard care Risk with preconception care
Pregnancy Study population not estimable 109
 (1 RCT) ⊕⊝⊝⊝
 Very low1,2 No pregnancies reported in 1 RCT
In 2 additional RCTs pregnancy was an exclusion criterion or was not clearly reported
0 per 1000 0 per 1000
 (0 to 0)
Hypertensive disorders of pregnancy Study population not estimable (0 studies)  
0 per 1000 0 per 1000
 (0 to 0)
Caesarean section Study population not estimable (0 studies)  
0 per 1000 0 per 1000
 (0 to 0)
Perineal trauma Study population not estimable (0 studies)  
0 per 1000 0 per 1000
 (0 to 0)
Gestational weight gain Study population not estimable (0 studies)  
0 per 1000 0 per 1000
 (0 to 0)
Cardiovascular health Study population not estimable (0 studies)  
0 per 1000 0 per 1000
 (0 to 0)
Induction of labour Study population not estimable (0 studies)  
0 per 1000 0 per 1000
 (0 to 0)
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: Confidence interval; RCT: randomised controlled trial; RR: Risk ratio
GRADE Working Group grades of evidenceHigh quality: we are very confident that the true effect lies close to that of the estimate of the effect
 Moderate quality: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
 Low quality: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect
 Very low quality: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect

1The study had design limitations (‐1).
 2No events and small sample size (‐2).