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Subcellular localizations of predicted and truncated TMTFs in COS-7 cells were detected using anti-Myc antibodies. Full-length proteins are localized to intracellular membrane compartments, but truncated forms (Δ) lacking predicted transmembrane segments accumulate in the nucleus. Nuclei are stained with Hoechst. (a) mouse MTJ1; (b) human DMRT2.
