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. 2019 Mar 7;4(5):e122943. doi: 10.1172/jci.insight.122943

Figure 8. Plt-β2M–/– mice have an early proreparative skewed monocyte response to MI.

Figure 8

(A) Plasma inflammatory protein array. WT mice had a day 3 post-MI increase in proinflammatory plasma proteins, whereas Plt-β2M–/– mice had a greater increase in proreparative plasma proteins. (B) Circulating monocytes were isolated from WT and Plt-β2M–/– mice before and 3 days after MI, and qPCR was performed for Cxcl1 and Il10. Monocytes from Plt-β2M–/– mice had less Cxcl1 and increased Il10 expression after MI compared with WT mice (n = 4, **P < 0.01, 1-way ANOVA with Bonferroni correction).