Cornell 1993.
Methods | Study type: RCT of body parts Randomisation method: computerised randomisation Blinding: double‐blind Intention‐to‐treat analysis used: yes |
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Participants |
Inclusion criteria of the trial
Exclusion criteria of the trial
Number of randomised participants: 30 in total Number of dropouts: 1 (3%) Sex: 14 males, 16 females Age (mean): 37.7 years Country: USA |
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Interventions |
Treatment
Comparator/s
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Outcomes |
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Notes | 1 of 2 included studies comparing mild steroids with each other. The adverse events rate was calculated from a table | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Computerised randomisation was used |
Allocation concealment (selection bias) | Unclear risk | No information was provided |
Similarity of the study groups (selection bias) | Unclear risk | Bilateral disease severity was not reported separately |
Blinding of participants (performance bias) | Low risk | Colour‐coded side‐labelled tubes were used |
Blinding of care providers (performance bias) | Unclear risk | Whilst the study was reported to be double‐blind, it was not clear who was blinded |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Whilst the study was reported to be double‐blind, it was not clear who was blinded |
Incomplete outcome data (attrition bias) All outcomes | Low risk | The number of dropouts was small |
Selective reporting (reporting bias) | Low risk | No selective reporting bias was identified |
Other bias | Unclear risk | The pharmaceutical industry supported the study, and the corresponding author was affiliated with the pharmaceutical industry |