Schaefer 2006.

Methods	Study design: parallel, 3‐arm RCT (1:1:1) Study duration: recruitment not reported Duration of follow‐up: 1 year
Participants	Setting: single centre Country: USA Recipients of primary cadaver or non‐HLA identical living donor kidney Number: treatment group (41); control group (39) Mean age ± SD (years): not reported Sex (M/F): not reported Exclusion criteria:
Interventions	Treatment group SRL trough levels: 8 to 12 ng/mL PRED MMF: 2 g/d Control group TAC trough levels: 8 to 12 ng/mL PRED MMF: 2 g/d Both groups Thymoglobulin induction
Outcomes	Graft survival BPAR at 1 year SCr at 3 months Hyperlipidaemia
Notes	Funding source: not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	High risk	Study was described as randomised, method of randomisation was not reported
Allocation concealment (selection bias)	High risk	Insufficient information to permit judgement
Blinding of participants and personnel (performance bias) All outcomes	High risk	Open‐label study
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Selective reporting (reporting bias)	Unclear risk	Reported all outcomes
Other bias	Unclear risk	Insufficient information to permit judgement