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. 2017 Jul 21;2017(7):CD006750. doi: 10.1002/14651858.CD006750.pub2

David‐Neto 2014.

Trial name or title A randomized, prospective study comparing everolimus/low tacrolimus with regular tacrolimus/MPS for the elderly renal transplant recipients
Methods
  • Parallel RCT

Participants
  • Elderly patients referred for kidney transplantation; 1 month post‐transplant

Interventions Treatment group
  • Low TAC trough levels: 2 to 4 ng/mL

  • EVL trough levels: 3 to 8 ng/mL


Control group
  • Regular TAC trough levels: 5 to12 ng/mL

  • MPS


Both groups
  • Steroids

  • ATG induction therapy: single dose 2 mg/kg

Outcomes
  • AR

  • DM

  • Infection

  • BK virus

  • CMV infection

Starting date 36 patients have been evaluated of the total 90 planned
Contact information David‐Neto, E
Notes