Skip to main content
. 2017 Aug 23;2017(8):CD007122. doi: 10.1002/14651858.CD007122.pub4

Summary of findings for the main comparison. 75 g OGTT versus 100 g OGTT for diagnosing GDM to improve maternal and infant health.

75 g oral glucose tolerance test (OGTT) versus 100 g OGTT for diagnosing gestational diabetes mellitus (GDM) to improve maternal and infant health
Patient or population: pregnant women at low or high risk of gestational diabetes
 Settings: 1 study, Nigeria
 Intervention: 75 g OGTT
Comparison: 100 g OGTT
Outcomes Illustrative comparative risks* (95% CI) Relative effect
 (95% CI) Number of participants
 (studies) Quality of the evidence
 (GRADE) Comments
Assumed risk Corresponding risk
100 g OGTT 75 g OGTT
Diagnosis of gestational diabetes Study population RR 2.55 
 (0.96 to 6.75) 248
 (1 study) ⊕⊝⊝⊝
 Very lowa,b Women who received the 75 g OGTT test were 2.55 times more likely to test positive for gestational diabetes.
45 per 1000 116 per 1000 
 (44 to 307)
Caesarean section See comment See comment Not estimable 0
 (0) See comment None of the included studies reported this outcome.
Macrosomia > 4.5 kg or as defined in trial See comment See comment Not estimable 0
 (0) See comment None of the included studies reported this outcome.
Long‐term type 2 diabetes maternal See comment See comment Not estimable 0
 (0) See comment None of the included studies reported this outcome.
Long‐term type 2 diabetes infant See comment See comment Not estimable 0
 (0) See comment None of the included studies reported this outcome.
Economic costs See comment See comment Not estimable 0
 (0) See comment None of the included studies reported this outcome.
*The basis for the assumed risk (e.g. median control group risk across studies) is the risk. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: Confidence interval; RR: Risk ratio.
GRADE Working Group grades of evidence.
 High quality: Further research is very unlikely to change our confidence in the estimate of effect.
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
 Very low quality: We are very uncertain about the estimate.

aOne study with design limitations (‐1).
 bWide confidence intervals crossing the line of no effect, few events and small sample size.