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| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 Overall survival | 4 | 579 | Hazard ratio (Fixed, 95% CI) | 0.74 [0.61, 0.89] |
| 2 Tumour response | 1 | Odds Ratio (M‐H, Fixed, 95% CI) | Subtotals only | |
| 3 Time to progression | 1 | Hazard Ratio (Fixed, 95% CI) | Subtotals only |
